General Cell Lines and Cell Cultures
ATCC Staphylococcus aureus; subsp. aureus
Staphylococcus aureus subsp. aureus strain FPR3757 was isolated from the wrist abscess of an HIV+ man with a history of IV drug use. This whole-genome sequenced bacterial culture is resistant to methicillin and oxacillin and can be used in drug discovery.
Biolegend TotalSeqTM-C0227 anti-mouse CD
TotalSeq™-C0227 anti-mouse CD122 (IL-2Rβ) [5H4]; Isotype: Rat IgG2a, κ; Reactivity: Mouse; Apps: PG; Size: 10 μg
ATCC Human Coxsackievirus A10; Strain: M.K.(Kowalik)
Human Coxsackievirus A 10 strain M.K. (Kowalik) is propagated in RD cells (ATCC CCL-136). This strain was isolated from the stool of a 7-year-old child in New York in 1950.
ATCC Trichophyton megninii; CDC 424
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
Eurofins Discoverx ChemiScreen TRH Thyrotropin-Releasing Hormone Receptor Stable Cell Line, 2 vials. (HTS126C)
The ChemiScreen TRH Thyrotropin-Releasing Hormone Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. TRH) based activation of TRHR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses TRHR alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of TRHR, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx Ready-to-Assay M2 Acetylcholine (Muscarinic) Receptor Frozen Cells, 2 Vials of Cells. (HTS115RTA)
The Ready-to-Assay M2 Acetylcholine (Muscarinic) Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. acetylcholine) based activation of CHRM2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CHRM2 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of CHRM2, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx ChemiBrite A2A Adenosine Receptor Stable Cell Line, 2 vials. (HTS048L)
The ChemiBrite A2A Adenosine Receptor cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of ADORA2A GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses ADORA2A alongside exogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. ChemiBrite cells also express a clytin variant, allowing for luminescent as well as fluorescent signal detection. Upon activation of ADORA2A, the resulting calcium activity can be assayed in either detection mode. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Enterobacter cloacae; Strain 1101152
Enterobacter cloacae strain 1101152 is a whole-genome sequenced bacterium that was isolated from a clinical specimen. This strain demonstrates resistance to ertapenem and imipenem and was confirmed by PCR to contain the blaKPC gene. It can be used in antimicrobial resistance research and multidrug testing.
ATCC HCT116-SLC35F2-KO-c2; Colorectal carcinoma; Human (Homo sapiens)
The HCT116-SLC35F2-KO-c2 cell line contains a +1 bp insertion in SLC35F2 gene and combined with the parental cell line and other HCT116 derivatives can be used in cancer drug screening.
There is a Permit requirement: License form needed to be completed Material Transfer Agreement Addendum for Screening Application
The forms are available here: https://www.atcc.org/support/order-support/permits-and-restrictions
ATCC Legionella pneumophila; subsp. pneumophila
Legionella pneumophila subsp. pneumophila strain 1169-MN-H was isolated from bronchial aspirate in Minnesota. This strain is whole-genome sequenced and known to be serotype 14. Explore the use of this strain in your respiratory disease research.
ATCC Acinetobacter baumannii
This multidrug-resistant strain of Acinetobacter baumannii was isolated in 2008 from a sputum sample in Maryland. This strain is propagated aerobically at 37°C in trypticase soy medium.
